Linagliptin 2.50mg + Metformin 500mg-
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Linatab M 2.5/500 Tablet is a combination medication used to manage type 2 diabetes.
Avoid consumption of alcohol while taking Linatab M 2.5/500 Tablet as it may increase the risk of unwanted side effects.
It is not known whether the use of Linatab M 2.5/500 Tablet could affect the unborn baby. Therefore, it should not be used during pregnancy unless recommended by your doctor.
It is not known whether the use of Linatab M 2.5/500 Tablet could pass through the breast milk. Therefore, it should be used in breastfeeding only if considered necessary by the physician
Linatab M 2.5/500 Tablet has no influence on your ability to drive or handle heavy tools or machines. However, do not drive or operate any machines if your ability is affected by LINAPIL M 2.5/500 TABLET.
Linatab M 2.5/500 Tablet is not recommended for use in patients with severely reduced kidney functions. Therefore, consult your doctor before taking it.
Linatab M 2.5/500 Tablet is not recommended for use in patients with severe liver problems. It should be used with caution in patients with gallstones. Therefore, consult your doctor before taking it.
LINAPIL M 2.5/500 TABLET is an antidiabetic medicine. It contains two medicines namely metformin and Linagliptin. Metformin makes the body more sensitive to insulin (a hormone involved in glucose metabolism). This helps our body cells to utilize more amount of the circulating blood glucose. Additionally, it can stop glucose production by the liver and reduce its absorption in the body.
Linagliptin controls blood sugar levels by blocking the actions of an enzyme called dipeptidyl peptidase (DPP)-4 that reduces insulin secretion in the body. Collectively, Linatab M 2.5/500 Tablet controls blood sugar levels and improves glycemic control in patients with type II diabetes.
Linagliptin is used to help people with type 2 diabetes regulate their blood sugar levels. DPP-4 (dipeptidyl peptidase-4) is an enzyme that degrades the incretin hormones GLP-1 (glucagon-like peptide-1) and GIP (glucagon-like peptide-1). Linagliptin is an inhibitor of DPP-4 (dipeptidyl peptidase-4) (glucose-dependent insulinotropic polypeptide). Linagliptin stimulates the release of insulin from pancreatic beta () cells in a glucose-dependent manner while reducing the production of glucagon from pancreatic alpha () cells in the blood, increasing the concentrations of active incretin hormones.
Metformin Hydrochloride is an antihyperglycemic medication of the biguanide class that is used to treat type 2 diabetes. Both baseline and postprandial plasma glucose levels are reduced. It has a different mode of action than sulfonylureas and does not cause hypoglycemia. Metformin Hydrochloride reduces hepatic glucose synthesis, intestinal glucose absorption, and insulin sensitivity by increasing peripheral glucose uptake and utilization.
The dosing instructions for Linagliptin & Metformin immediate-release and extended-release tablets are as follows:
Linagliptin & Metformin Immediate-Release Tablet:
Linagliptin & Metformin Extended-Release Tablet:
Please note that the extended-release tablet is taken once daily, while the immediate-release tablet may be taken twice daily, as prescribed by your healthcare provider. Always follow your doctor's instructions for the correct dosage and timing of these medications.
Linatab M 2.5/500 Tablet is a medication that can interact with various drugs, foods, and medical conditions. Here's a summary of these interactions:
Drug-Drug Interactions: Linatab M 2.5/500 Tablet can interact with several other medications, including:
It's important to inform your healthcare provider about all the medications you are taking to avoid potential interactions.
Drug-Food Interactions: Excessive consumption of alcoholic beverages while taking Linatab M 2.5/500 Tablet can increase the risk of a serious condition called Lactic Acidosis. It is advisable to avoid excessive alcohol intake while on this medication.
Drug-Disease Interactions: Individuals with certain medical conditions should exercise caution when taking Linatab M 2.5/500 Tablets. These conditions include:
If you have any of these medical conditions, it's essential to discuss the use of this medication with your doctor, as special monitoring or dosage adjustments may be necessary to ensure your safety and effectiveness of treatment.
Metformin Hydrochloride is primarily eliminated by the kidneys, and although Linagliptin has low renal excretion, severe renal impairment can increase the risk of Metformin Hydrochloride accumulation and lactic acidosis. Therefore, individuals with renal impairment should avoid this combination medications. Other contraindications include acute or chronic metabolic acidosis (such as diabetic ketoacidosis) and hypersensitivity to either Linagliptin or Metformin Hydrochloride. It's crucial for individuals with these conditions to refrain from using this medication.
Because there are no sufficient and well-controlled trials in pregnant women with this combination or its separate components, it should only be taken if obviously needed during pregnancy. When given to a nursing woman, extreme caution should be exercised.
Linatab M 2.5/500 Tablet comes with several important precautions and considerations:
Keep away from light and heat in a dry area. Keep out of children's reach.
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accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
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everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
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